Genfibrozil-hypolipidaemic drugs and its therapeutic uses

                                   

INTRODUCTION-

A lipid regulating agent that lowers elevated serum lipids primarily by dedcreasing serum triglyceride with a variable reduction in total cholesterol.

These decreases occur primarily in the VLDL fractions and less frequently in the LDL fraction.

 THERAPEUTIC USES-

* Used to decrese level of triglyceride.

 SIDE EFFECTS-

* Hives

* Difficulty in breathing

* Swelling of face, lips, tongue or throat.

DRUG DRUG INTERACTION-

* Gemfibrozil+Acipimox=Acipimox may increase the myopathic rhabdomyolysis activities of Gemfibrozil.

* Gemfibrozil+Agomilatine=The serum concentration of Agomilatine can be increased when it is combined with Gemfibrozil.

REFERENCE- Tripathi K.D. "Essentials of Medical Pharmacology", 7th Edition, page no- 639