METHOCARBAMOL
DESCRIPTION:
Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under
the trade name Robax, it
is marketed by Actient Pharmaceuticals in the United States and Pfizer in Canada. The mechanism of action of
methocarbamol is currently unknown, but may involve the inhibition of carbonic
anhydrase. The muscle relaxant effects of methocarbamol
are largely attributed to central depressant effects;however, peripheral
Side-effects
Potential side-effects include: drowsiness,
dizziness, clumsiness (ataxia),
upset stomach, flushing, blurred vision, and fever. Bothtachycardia (fast
heart rate) and bradycardia (slow
heart rate) have been reported;[6][7] these
can be serious. Other serious side-effects include the development of a
Interaction
Always tell your doctor about all medications you're taking,
including other prescription drugs, over-the-counter drugs, and any vitamins,
diet supplements, or herbal remedies.
Any drug that suppresses your central nervous system may interact
with methocarbamol. This includes drugs used for seizures, pain, depression, cough and colds, sleep
issues, and anxiety.
severe skin rash or itching, fainting, jaundice, persistent
nausea/vomiting, stomach/abdominal pain, mental/mood changes, trouble
urinating, and signs of infection. If taken in large amounts at once or more
than directed or as prescribed, dysphoria or suicidal thoughts may occur.
Methocarbamol Overdose
Overdosing happens more
frequently when methocarbamol is used with alcohol or another sedative drug.
Symptoms of an overdose
may include:
- Nausea
- Severe drowsiness
- Blurred vision
- Low blood pressure
- Seizure
- Loss of consciousness
REFERANCE- Tripathi K.D,"Essentials of medical pharmacology",7th edition,page no-357
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