Saturday, February 17, 2018

Meropenem-Antimicrobial drug


MEROPENEM

Description: It is a broad spectrum carbapenim antibiotic. It is active against gram positive and gram negative bacteria.
CLASS- THIENAMYCINS

Uses: To treat infections such as bacterial meningitis, abdominal infections, and complicated skin and soft tissue infections caused by susceptible organism

Adverse Drug Reactions: Pain and inflammation at injection site, rash, constipation, diarrhea, nausea, vomiting, headache

Drug-Drug Interactions: 
Meropenem+picosulfuric acid=decreased efficacy of picosulfuric acid
Meropenem+probenecid=increased serum concentration of meropenem

Reference: Tripathi KD," Essentials of Medical Pharmacology", 7th edition,page no- 731.

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