MEPACRINE
(quinacrine)
Description:
It is an acridine derivative formerly widely used as an antimalarial bit superseded by chloroquine in recent years.
CLASS-ACRIDINES
Adverse Drug Reactions:
Dizziness, headache, CNS stimulation, epilepsy; nausea & vomiting; discoloration of the skin, blue-black discolouration of the palate and nails; liver toxicity and anemia
MEPACRINE
(quinacrine)
Uses:
For the treatment of giardiasis and cutaneous leishmaniasis, management of malignant effusions, as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent.
Adverse Drug Reactions: Dizziness, headache, CNS stimulation, epilepsy; nausea & vomiting; discoloration of the skin, blue-black discolouration of the palate and nails; liver toxicity and anemia
Reference-Tripathi K,D,"Essentials of medical pharmacology",7th edition,page no-825
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