Tuesday, February 20, 2018

ISOPROPAMIDE - ANTICHOLINERGIC DRUG its side effects and uses

DESCRIPTION


PHARMACOLOGY-

Isopropamide is a long-acting quaternary anticholinergic drug. It is used in the treatment of peptic ulcer and other gastrointestinal disorders marked by hyperacidity and hypermotility.


MECHANISM OF ACTION-

Anticholinergics are a class of medications that inhibit parasympathetic nerve impulses by selectively blocking the binding of the neurotransmitter acetylcholine to its receptor in nerve cells. The nerve fibers of the parasympathetic system are responsible for the involuntary movements of smooth muscles present in the gastrointestinal tract. Inhibition here decreases acidity and motility, aiding in the treatment of gastrointestinal disorders.

SIDE EFFECTS-
Decreased Sweating Less Severe,Dry Mouth Less Severe,Incomplete or Infrequent Bowel Movements, Confused Severe,Hives Severe,Increased Pressure in the Eye Severe,Inflammation of Skin caused by an Allergy Severe,Rash Severe,Blurred Vision Less Severe,Difficult or Painful Urination Less Severe,Dilated Pupil Less Severe,Drowsiness.

DRUG DRUG INTERACTION-
Isopropamide may interact with the following drugs and products:
1. Adrenaline
2. Alcohol
3. Antidepressants
4. Guanethidine
5. Levodopa
6. Lithium
7. Narcotic pain medication
8. Thyroxine
9. Trazodone

USES-
ISopropamide  is used in the treatment, control, prevention, & improvement of the following diseases, conditions and symptOMS-
Cold
Muscular contraction that causes pain
Peptic ulcer
Inflammation of nasal membrane
Depression
Nausea
Vomiting
Emotional instability



REFERENCE:


Tripathi K.D,"Essentials of medical pharmacology",7th edition,page no.117

1 comment:

  1. How I became a happy woman again
    With tears of joy and happiness I am giving out my testimony to all viewers online, my problem with Stomach Cancer stage IB and HIV has caused me many pains and sadness especially in my family.
    I was so afraid of loosing my life, I suffered the embarrassment of visiting
    therapy hundreds of times, unfortunately they did not find a definitive solution to my problem, I cried all day and night, do I have to live my life this way? I searched all true the internet for care, I was scammed by internet fraudsters times without numbers… until a friend of mine who stays in the UK introduced me to a friend of hers who was cured of the same disease, and she introduced me to Dr Itua who cured her from Breast Cancer by this email/WhatsApp +2348149277967, drituaherbalcenter@gmail.com I contacted him and he promised that all will be fine and I had faith.He sent me his herbal medicines through Courier service and I was instructed on how to drink it for three weeks to cure,I followed the instructions given to me and Today am a happy woman again. He cures all kinds of diseases.

    ReplyDelete