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Thursday, February 15, 2018

Galantamine - drugs acting on ans and its therapeutic uses


It is an alkaloid obtained synthetically or from the bulbs or flowers of Galanthus caucasius.
PHARMACOKINETIC
• Absorption:  well absorbed orally.
• Metabolism: partially hepatic. 
• Excretion: renal.
• Half life: 7 hrs.

THERAPEUTIC USES
• It is used in treatment of dementia caused by Alzheimer’s disease.
• Treatment of mild cognitive impairment (MCI).

ADVERSE EFFECTS
• Bradycardia
• Syncope (fainting).
• Seizures
• Bleeding in stomach and intestine.


REFERENCE- Tripathi K.D. "Essentials of Medical Pharmacology", 7th Edition, page no- 108
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