Search This Blog

Sunday, March 18, 2018

Riboflavin


Mechanism of action
Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.


Reference: Tripathi K.D., "Essentials of Pharmacology", published by jaypee brother publication, New Delhi, seventh edition, page no:-606, 913, 914.




at
Labels:

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)

 

  • doxycycline
    Doxycycline   inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit.   Doxycycline   has bacteriostatic activity a...
  • NIFEDIPINE
    NIFEDIPINE: MECHANISM OF ACTION- •    It’s a prototype DHP with a rapid onset of action with short duration. •    It’s a calcium channel...
  • Metyrapone
    Metyrapone blocks cortisol synthesis by reversibly inhibiting steroid-11 beta hydroxylase. This stimulates ACTH secretion, which in tur...