Wednesday, March 21, 2018

Hydroxyzine


Mechanism of action of Hydroxyzine-

Hydroxyzine is a histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.


Reference-
Tripathi K.D “Essentials of Medical Pharmacology", published by Jaypee brothers, New Delhi, 7th edition, page no. 164,165,467

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