Mechanism of action of
Hydroxyzine-
Hydroxyzine is a histamine H1 receptor antagonist
that is effective in the treatment of chronic urticaria, dermatitis, and
histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does
cause drowsiness. It is also effective as an antiemetic, for relief of anxiety
and tension, and as a sedative.
Reference-
Tripathi K.D “Essentials of Medical Pharmacology", published
by Jaypee brothers, New Delhi, 7th edition, page no. 164,165,467
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