Sunday, March 18, 2018

pentazocine-Mechanism of action

Mechanism of action of pentazocine:-  
Pentazocine is a potent analgesic which when administered orally in a 50 mg dose appears equivalent in analgesic effect to 60 mg (1 grain) of codeine. The evidence suggests that pentazocine antagonizes the opioid effects by competing for the same receptor sites, especially the opioid mu receptor.

Tripathi k.d.,"Essentials of Pharmacology",published by jaypee brother publication ,new dehli,seventh edition,

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