Wednesday, March 21, 2018

Ibuprofen


www.ebmconsult.com

Mechanism of action of Ibuprofen

Ibuprofen is a non-selective inhibitor of an enzyme called cyclooxygenase (COX), which is required for the synthesis of prostaglandins via the arachidonic acid pathway. COX is needed to convert arachidonic acid to prostaglandin H2 (PGH2) in the body.


Reference-
Tripathi K.D “Essentials of Medical Pharmacology", published by Jaypee brothers, New Delhi, 7th edition, page no. 199-200,208,209.

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