Wednesday, March 21, 2018

Ibutilide


Mechanism of action of Ibutilide-

Ibutilide's unique mechanism works by an activation of a specific inward sodium current, thus producing its therapeutic response in which a prolonged actionpotential increases myocytes' cardiac refractoriness in case of atrial fibrillation and flutter.

Reference-
Tripathi K.D “Essentials of Medical Pharmacology", published by Jaypee brothers, New Delhi, 7th edition, page no. 529,535.

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