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Friday, March 16, 2018

Penfluridol- mechanism of action


Mechanism of action of penfluridol: - 
Penfluridol binds to the dopamine receptor (D1, D2, D3 &D4).It exerts its antipsychotic activity by blocking the dopamine projections in the limbic system and in mesocortical area. Peripherally and centrally it acts as a competitive Dopamine antagonist.



Reference:-
Tripathi k.d.,"Essentials of Pharmacology",published by jaypee brother publication ,new dehli,seventh edition,p.no:-441
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