Sunday, April 8, 2018


Midazolam- it is thought that the action of  benzodiazepenes such as midazolaam are mediated through the inhibitory neurotransmitter gamma-aminobutyric acid(GABA), which is one of the major inhibitory neurotransmitter in the brain. BZD’s increase the activity of  GABA, thereby producing a calming effect, relaxing skeletal muscles and inducing sleep. BZD’s bind to the benzodiazapene site on GABA-A receptors, which potentiates the effect of  GABA by increasing the frequency of chloride channel opening.

Reference: Tripathi K.D; Essentials of Clinical Pharmacology; Jaypee Brothers Medical Publishers; Seventh edition; Page no.378, 383, 405


  1. Great Article! Thanks for sharing this types of article is very helpful for us! If you have any type of pain like chronic pain, back pain etc.
    Best Pharmacy Shop
    Order Pharmacy Online
    Buy Caverta Online
    Buy Abamune Online
    Buy Acaprol Online
    Buy Admenta Online
    Order Admenta Online

  2. This particular papers fabulous, and My spouse and i enjoy each of the perform that you have placed into this. I’m sure that you will be making a really useful place. I has been additionally pleased. Good perform! Michael telvi