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Wednesday, April 11, 2018

DOXAZOCIN


The mechanism of action of DOXAZOCIN  selective blockade of the alpha1 (postjunctional) subtype of adrenergic receptors. Studies in normal human subjects have shown that doxazosin competitively antagonized the pressor effects of phenylephrine (an alpha1 agonist) and the systolic pressor effect of norepinephrine.

REFERENCE-KD TRIPATHI, JAYPEE BROTHERS MEDICAL PUBLISHERS PVT.LTD 7TH EDITION, REPRINT 2001,PG NO.:142,144,565.



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