Sunday, April 8, 2018

Febuxostat


Febuxostat is a non-purine-selective inhibitor of xanthine oxidase. It works by non-competitively blocking the molybdenum pterin center which is the active site on xanthine oxidase. Xanthine oxidase is needed to successively oxidase both hypoxanthine and xanthine to uric acid. Hance, febuxostat inhibits xanthine oxidase, therefore reducing production of uric acid. Febuxostat inhibits both oxidised as well as reduced form of xanthine oxidase because of which febuxostat can't be easily displaced from the molybdenum pterin site.

Reference: Tripathi KD; Essentials of Clinical Pharmacology; Jaypee Brothers Medical Publishers; seventh edition; Page no: 213



11 comments:

  1. Great Article! Thanks for sharing this types of article is very helpful for us! If you have any type of pain like chronic pain, back pain etc.
    Best Pharmacy Shop
    Order Pharmacy Online
    Buy Caverta Online
    Buy Abamune Online
    Buy Acaprol Online
    Buy Admenta Online
    Order Admenta Online

    ReplyDelete
  2. Have read many blogs in the net but have never come across such a well written blog. Good work keep it up.Buy Waklert Online

    ReplyDelete