Saturday, April 7, 2018

mechanism of action of mephentermine

  •  it is a sympathomimatic agent, used to maintain blood pressure in hypertension.
  •  mechanism of action of mephentermine involves direct stimulation of B-adrergic receptors causing the release of norepinephrine, from its storage site.
  •  it has a positive intropic effect on the myocardium. 
  •  in this condition crdiac output and systolic and diastolic pressures are increased in most of the cases.
  •  large dose can depress myocardium and produce central nervous system(CNS) effects.

reference:Tripathi K.D., “Essentials of Medical Pharmacology”, Jaypee brothers medical publishers, Seventh edition, New Delhi, page no.564.

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