Wednesday, April 11, 2018

DOXACURIUM


Doxacurium  binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission (non-depolarizing). This action is antagonized by acetylcholinesterase inhibitors, such as neostigmine. Doxacurium  is a long-acting, nondepolarizing skeletal muscle relaxant. The neuromuscular block produced by doxacurium  may be antagonized by anticholinesterase agents. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at reversal, the longer the time and the greater the dose of anticholinesterase required for recovery of neuromuscular function. Doxacurium  is approximately 2.5 to 3 times more potent than pancuronium and 10 to 12 times more potent than metocurine.

REFERENCE-KD TRIPATHI, JAYPEE BROTHERS MEDICAL PUBLISHERS PVT.LTD 7TH EDITION, REPRINT 2001,PG NO.:347,352,353.


9 comments:

  1. Great Article! Thanks for sharing this types of article is very helpful for us! If you have any type of pain like chronic pain, back pain etc.
    Best Pharmacy Shop
    Order Pharmacy Online
    Buy Caverta Online
    Buy Abamune Online
    Buy Acaprol Online
    Buy Admenta Online
    Order Admenta Online

    ReplyDelete